Pyrazole-based ion-channel inhibitors are highly selective drugs with potential to cure various diseases. Employing high-temperature reaction conditions in sealed vials the multistep synthesis can be significantly enhanced resulting in short time reaction steps.
The reaction sequence to the potential channel inhibitor involves common standard chemical transformation procedures. This makes it a beneficial example for teaching modern synthesis techniques...
UK productivity hindered by digital skills deficit – report
This is a bit of a nebulous subject. There are several sub-disciplines of 'digital skills' which all need different approaches. ...