The Grignard reaction is a powerful, frequently used organometallic transformation to add important structural motifs to carbonyl compounds resulting in secondary or tertiary alcohols. Since usually the low boiling THF is used as a solvent, closed vessel conditions and elevated temperatures can significantly enhance the reaction. This is best done in a conventional synthesis reactor.
UK productivity hindered by digital skills deficit – report
This is a bit of a nebulous subject. There are several sub-disciplines of 'digital skills' which all need different approaches. ...