Quaternary ammonium salts were used as ethylene source for the direct ethylation of benzylic amines. Simple Hofmann elimination delivers the olefin in situ avoiding the need for gaseous reagents and autoclave technology. The alkylation takes place under rhodium catalysis, requiring inert atmosphere, with exclusive selectivity for the C(sp3)-H bond.
UK productivity hindered by digital skills deficit – report
This is a bit of a nebulous subject. There are several sub-disciplines of 'digital skills' which all need different approaches. ...