Closed Vessel Digestion for Elemental Impurities Analysis of Osmium According to ICH Q3D, USP <232>, <233> and Ph. Eur. 5.20 with PDC

Using Multiwave 7000 simultaneously facilitates the digestion of different sample matrices under full GMP compliance and even generates digestion solutions enabling the accurate and reproducible determination of very difficult to determine Osmium.

This report applies Multiwave 7000 and after the digestion a dilution with a stabilization solution containing acetic acid, ascorbic acid and thiourea in order to stabilize Os in the oxidizing environment during the sample preparation of one pharmaceutical product and one API.

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