Sensor could aid weight loss through acetone assessments

Developed at NTT DOCOMO Research Laboratories, the portable, pocket-sized sensor works by measuring increased levels of acetone on the breath, which is said to be a good indicator of when the body has begun to break down fat.

The device has been presented today, 25 July, in IOP Publishing’s Journal of Breath Research.

Acetone is primarily produced in the blood when fat is broken down; however, it is also expelled through alveoli in the lungs during exhalation and is present in exhaled breath.

This new device, which is reportedly capable of detecting acetone concentrations in the range of 0.2 to 50 parts-per-million, is 10 cm long, weighs 125g and requires two AA batteries to operate.

The device consists of a pressure sensor to detect the exhaled breath and two types of semiconductor-based gas sensors to detect acetone.

After a user blows into the device, the acetone concentration levels can be calculated and sent to a smartphone, either by Bluetooth or a cable, within 10 seconds.

Methodology

In their study, the researchers recruited 17 healthy adult volunteers (11 men and six women), whose body mass indexes (BMIs) were above the Japanese standard, to test the device.

The volunteers were split into three groups, the first of which carried on with their normal life and were not restricted to a specific numbers of  calories in their diet and not required to take part in exercise.

The second group were required to take part in light exercise, such as jogging or fast walking, for 30-60 minutes a day and the final group were required to take part in the same exercise routine and also consume a limited number of calories in their diet each day.

The experiment lasted 14 days and on each day before breakfast, the volunteers were required to measure their body weight, body fat percentage and breath acetone concentrations using the portable device and a standard instrument for comparison.

Results showed that the volunteers in the first two groups - those leading a normal life and those performing daily exercise - were not able to lose significant amounts of fat. Their breath acetone concentrations also remained constant.

The volunteers in the third group who followed the exercise regime and had their calorific intake restricted were able to lose significant amounts of  fat and their breath acetone concentrations were increased significantly.

Effectiveness

In a statement, principal investigator Satoshi Hiyama, said, ‘Because obesity increases the risk of lifestyle-related illnesses, enabling users to monitor the state of fat burning could play a pivotal role in daily diet management. Current standard methods, however, are still not practically suitable for point-of-care instrumentation for diet-conscious people who wish to monitor their own fat metabolism at home or outside’

‘Considering that the effect of dieting could be estimated from changes in breath acetone concentrations, we’ve shown that our prototype is a practical and alternative checker that can be used in individual dieting  programmes.’ 

‘It is also known that when diabetes is out of control, patients have elevated levels of breath acetone. It is possible that our prototype could be used to assess how diabetic control is being managed at home.’